Thursday, June 9, 2011

Shout out to Scientists

Trying to study today, I came across the following tidbit that inspired a bit of appreciation for biochemistry:

Patient discussion about fructose 1,6-bisphosphate aldolase.

Q. what is more healthy, brown sugar or fruit sugar?

A. latest researches indicates that there are no difference between white sugar and brow sugar. they are both contain carbohydrates, which is bad for you.
about fructose - i don't think the difference is too big, one difference is that the intestine absorbs the glucose with other receptor

Q. What difference does fructose makes to a diabetic with respect to glucose? I am diabetic with type 2 NIDDM. My colleague with the same NIDDM type2 has a better glycemic control than me. He follows strict diet. He prefers fructose sugar and avoids other sugar as much as possible. He suggested me the same. What difference does fructose makes to a diabetic with respect to glucose?

A. All carbohydrates—like starch and sugars like dextrose, maltose and glucose must be controlled for high consumption by a diabetic. Whereas fructose sugar had a slight different metabolic route inside the body and it does not requires insulin. Glucose requires insulin. As a diabetic lacks insulin production; the glucose increases the sugar level of the body but fructose is out of this system of functioning by our body and makes a diabetic to control it well. The energy level of glucose and fructose are almost similar.

http://medical-dictionary.thefreedictionary.com/fructose+1,6-bisphosphate+aldolase



I still don't understand it. But at least I know what it is others understand. I don't have to just trust that they know, but I know what they are looking at and "how they know" what they do about diet and such. It all goes down to the cellular level biochemical reactions, they are not making it up.

Thank you people out there who understand this stuff and who are doing tedious research to figure out biochemistry (how and why things affect our bodies and living organisms). Let me know when you make a conclusion that has practical application and relevance to my life. Oh wait, that happens all the time (medicine, nutrition etc). Sweet.

Wednesday, June 8, 2011

Biochemistry BARF


phosphatidylethanolamine
phosphatidylglycerol
sphingomyelin
CDP-diacylglycerol
eukaratoic
glycerolphospholipid synthesis
cardiolipin
glyoxylate cycle
Apoliopoproteins
perilipins
methylmalonyl-CoA epimerase
5' -deoxyadenosylcobalamin
Ubiquinone
adenine nucleotide translocase
xenobiotics (compounds synthesized industrially)

"Sucrose is synthesized int he cytosol, begining with dihydroxyacetone phosphate and glyceraldehyde 3-phosphate exported from the chloroplast. After condensation of two triose phosphates to form fructose 1,6-biphosphate (catalyzed by aldolase), hydrolysis by fructose 1,6-biphosphatase yields fructose 6-phosphate." (pg.792, Lehinger Principles of Biochemistry, 5th Edition).

"A cytosolic isozyme of malate dehydrogenase oxidizes malatate to oxaloacetate, a precursor for glucongenesis."

Do you know what this means?
Me either.

Pretty sure I would drop out of school right now if I had more than 7 days left.
Pray I pass.

Biochemistry BARF


phosphatidylethanolamine
phosphatidylglycerol
sphingomyelin
CDP-diacylglycerol
eukaratoic
glycerolphospholipid synthesis
cardiolipin
glyoxylate cycle
Apoliopoproteins
perilipins
methylmalonyl-CoA epimerase
5' -deoxyadenosylcobalamin
Ubiquinone
adenine nucleotide translocase
xenobiotics (compounds synthesized industrially)

"Sucrose is synthesized in the cytosol, begining with dihydroxyacetone phosphate and glyceraldehyde 3-phosphate exported from the chloroplast. After condensation of two triose phosphates to form fructose 1,6-biphosphate (catalyzed by aldolase), hydrolysis by fructose 1,6-biphosphatase yields fructose 6-phosphate." (pg.792, Lehinger Principles of Biochemistry, 5th Edition).

"A cytosolic isozyme of malate dehydrogenase oxidizes malatate to oxaloacetate, a precursor for glucongenesis."

Do you know what this means?
Me either.

Pretty sure I would drop out of school right now if I had more than 7 days left.
Pray I pass.